Fri, 3 July 2020
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Briefly, some of us have variable activities of important enzymes that metabolize estrogens in our liver.
Imbalances in these enzymes create “sticky estrogens” that can cause mutations in DNA which, over time, can lead to cancer.
Here are the full details:
Here are some important time stamps!
07:18 How estrogens become carcinogens 10:40 Higher levels of estrogen-DNA adducts in women with ovarian cancer 13:50 If your catechol-O-methyltransferase is not working well, your catechol estrogen can go on to become a quinone and react with DNA. 20:36 Why estrogen-DNA are analogous to taking a step off the DNA ladder 27:02 Men with prostate cancer have high levels of estrogen-DNA adducts.
Hope you gather some insights from this discussion,
Mike
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