High Intensity Health Radio with Mike Mutzel, MS

Gene expert Dr. Ben Lynch helps us to better understand which flavor of genes we  have and how that may affect things like food cravings, fat adaptation and hormone  metabolism. 


If you crave sugar and sweets, it’s not that you’re broken, he says. You may have a flavor of COMT or MAO that influences neurotransmitter breakdown and metabolism. 

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Now for today’s show…


I think this knowledge is super helpful when it comes to personalizing a diet and exercise program that will work for you in the long term. 

Dr. Lynch and I also dive into the methylation cycle and how it is involved in the 
synthesis of many key molecules needed to burn fat for fuel

Hope you enjoy the convo.

Show notes and video: https://highintensityhealth.com/2017

 

 

He’s got a great new book out, called Dirty Genes—I posted a quick summary of that, here: https://highintensityhealth.com/2017


Key Takeaways:

05:21 Methylation occurs in every cell all over the body. In the brain it makes neurotransmitters.
06:23 Carnitine is required during intermittent fasting, ketosis and general fat consumption.
07:39 One sign that you are not methylating well would be an active startle reflex.
09:24 Methylation’s primary job is to turn off genes. It does turn some on.
10:17 Most methyl groups are found in protein. The cobalamins produced by gut bacteria is used only by our gut bacteria.
13:40 Stop taking folic acid.
21:24 Methylation plays a minor but significant role in detoxification.
23:49 Foods to support detoxification include cruciferous vegetables, eggs, and broccoli and radish sprouts eaten together.
27:05 If you are having high reactive nitrogen species or high reactive oxygen species, your attempts at keto will fail.
29:04 If NQO1 is not functioning well, CoQ10, vitamin C, glutathione and vitamin E supplements may do harm.
29:46 High dopamine quinone levels are found in those of us with dementia, neurological disorders, and Parkinson’s. The vitamin needed to run NQO1 is riboflavin.
32:00 Estrogen quinones lead to estrogen sensitive cancers.
32:26 Excessive levels of dopamine in your brain will lead to more norepinephrine and epinephrine.
40:30 If you have a faster COMT, eat more protein and perhaps supplement with more tyrosine.
42:00 Fast COMT/inattentive folks fidget and move to stimulate their brains to make dopamine.
43:37 Slower COMT is associated with PMS, estrogen based cancers, insomnia and higher blood pressures.
50:15 A fast MAOA depletes your serotonin levels and burns through your tryptophan.
56:34 You don’t have to be on a ketogenic diet to burn fat.
01:00:03 Excessive exercise and overtraining causes inflammation, which causes increased blood sugar, which kicks you out of ketosis.
01:03:40 The other Super Seven Genes
01:05:28 Check your arsenic levels.
01:06:20 Stop thinking disease and focus on function.
01:09:35 Every action you take cleans your genes or dirties your genes.
01:10:45 Dr. Lynch’s morning routine is one of personal growth and deep work.
01:16:00 Dr. Lynch’s desert island nutrient is liposomal glutathione.
01:17:05 Dr. Lynch’s elevator pitch: The cure for all conditions is preventing it.

 

 

Direct download: 217_Ben_Lynch_Methylation__Metabolism.mp3
Category:general -- posted at: 11:12am PDT

Dr. Ted Naiman is a low-carb enthusiast, athlete and physician in the Seattle area. He discusses how and why we get fat, and how to become better fat burners.

Hope you enjoy the convo.

This episode is brought to you by:

Try Somnifix.com, the worlds only hypoallergenic mouth tape, studied by Harvard Scientists.
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Health IQ, an insurance company that helps health conscious people like weightlifters, cyclist, keto dieters and vegetarians get lower rates on their life insurance.

Get a Free Quote: http://healthiq.com/HIH

 Show notes and video: https://highintensityhealth.com/2016

Key Time Stamps

02:32 Insulin prevents us from burning fat for fuel.
04:36 You become insulin resistant when your fat cells are full and you do not have anywhere to store fat.
05:12 Why did you overfill your fat cells? They overfill when you eat carbohydrates and fat together, displacing fat oxidation.
08:11 How can you burn more fat and store less fat? You can oxidize more fat by restricting exogenous glucose.
09:12 The bigger you get, the faster you are going to die.
10:56 Metabolically obese normal weight individuals are an exception to the waist/height ratio.
13:53 Your personal fat threshold is genetically built in.
15:34 Becoming fat can be protective.
17:12 Everyone has fatty liver now.
17:49 If you have an abundance of free fatty acids in your blood and it is being rejected by your cells and tissues, your body goes to war with itself.
19:26 You can reverse insulin resistance by eating either an extremely low fat diet or an extremely low carb diet. Studie
22:06 If you are fat to begin with, you should do the low carb/high fat approach.
22:46 If you already have very low body fat, if you eat a high carb/low fat diet, you will remain thin.
23:27 For someone who is very overweight and very insulin resistant, a protein heavy/low carb diet is Dr. Naimans recommendation.
25:03 You will lose just as much lean/muscle mass as fat mass with fasting or undereating calories.
26:53 If you dont hit your protein target, you will overeat energy as carbs or fats to get enough protein.
32:19 What about vegetarians and vegans with protein?
36:13 You should get to ketosis with carb restriction.
39:20 Muscle is the organ of longevity.
39:26 Keep your insulin pulsatile.
42:21 Ambient temperature is a huge factor in diabetes.
47:56 Always start with diet. Take one meal at a time and replace your carbs with protein and fat.
50:20 Dr. Naiman has no morning routine, though he does drink cold brewed coffee. He fasts in the morning, not eating until about 1 p.m.
51:37 Dr. Naimans singular favorite exercise is the muscle up. It is the best upper body exercise.
54:29 Dr. Naiman takes no supplements and rarely recommends them.
56:35 Dr. Naimans elevator pitch is to put protein first. Ruminant agriculture on natural grasslands would turn around obesity and diabetes, and it helps the environment.

Show notes and video: https://highintensityhealth.com/2016

 

 

Direct download: 216_Ted_Naiman_MD.mp3
Category:general -- posted at: 11:26am PDT

Dental expert Steven Lin, DDS, says, “There is nearly no chronic disease that you can’t reconnect back to the mouth.”

He’s spearheading a much-needed narrative about the importance of oral-systemic health.

Get the show notes: https://highintensityhealth.com/215

This episode is brought to you by:

Try Somnifix.com, the world’s only hypoallergenic mouth tape, developed by Harvard Scientists.

https://www.somnifix.com

Health IQ, an insurance company that helps health conscious people like weightlifters, cyclist, keto dieters and vegetarians get lower rates on their life insurance.

Get a Free Quote: http://healthiq.com/HIH

 

Talk of gut bacteria and leaky gut has taken center stage when it comes to health and wellness.

But technically, the gut starts in the mouth (it’s the entry point of the alimentary canal).

Every swallow of digestive secretions influences the microbiome below it … and possibly above it, too.

Oral bacteria have been found in the brains of Alzheimer’s patients and the hearts of patients with cardiovascular disease.

Dr. Steven Lin shares tips and insights about:

- Oral health-improving tactics that can enhance sleep

- Nutritional strategies that can affect your child’s facial development and breathing patterns

- The link between oral health and heart disease

- How to find a good, holistic dentist

Get the show notes: https://highintensityhealth.com/215

 

Direct download: 215_Steven_Lin_DDS.mp3
Category:general -- posted at: 1:27pm PDT

Valter summarizes the findings and discoveries from his lifelong interest and academic research in fields of longevity and aging.

This episode is brought to you by:

Try Somnifix.com, the world’s only hypoallergenic mouth tape, developed by Harvard Scientists.

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Health IQ, an insurance company that helps health conscious people like weightlifters, cyclist, keto dieters and vegetarians get lower rates on their life insurance.

Get a Free Quote: http://healthiq.com/HIH

Key Takeaways and Timestamps from the discussion:  

02:26 Growth hormone gene mutations impact longevity and protection from chronic disease.

04:58 Ageing and age-related chronic diseases can be regulated through genetic intervention or with nutritional interventions.

07:20 Starvation has a much greater and faster impact than temporary caloric restriction.

09:24 Weaker cells are consumed during a fasting mimicry diet.

11:50 Most organisms starve most of the time.

14:26 Low protein helps people under the age of 65 and hurts people over the age of 65.

18:09 Proteins control growth factor/growth hormone which controls IGF-1, which also controls mTOR.

19:31 Athletes need to have enough protein in the regeneration refeed.

23:39 Just adhering to the Fasting Mimicry Diet 5 days out of 30 is enough to have a significant drop in IGF-1, cholesterol, triglycerides, blood pressure, fasting glucose, and inflammation.

27:46 If you fast over 12 hours every day, you have a two-fold increase in the risk of needing to have your gallbladder removed

30:03 Fasting for 14 to 16 hours has benefits: increased ketone bodies, weight loss, and metabolic advantages.

30:38 Consuming ketone bodies and fatty acids on top of a normal diet is a mistake. It confuses your metabolism. Long term repercussions are unknown.

36:26 Fasting Mimicry Diet is the result of years of researching the connection of each component of food and the genes that regulate ageing and regeneration.

39:25 Dr. Longo’s Morning Routine: He drinks a mix of black tea and green tea with a whole lemon and preserved fruit. He rides stationary bike and breaks his fast after exercise.

42:44 Dr. Longo’s Desert Island Nutrient:

46:32 Dr. Longo’s Elevator Pitch: Implement The Fasting Mimicry Diet through the population.

 

Direct download: 214_Longo_Longo_PhD_longevity_diet.mp3
Category:general -- posted at: 7:06pm PDT

Rangan’s the author of The 4 Pillar plan, featured expert on BBC, sought after doctor and globally recognized Functional Medicine expert for his ability to simplify, the often overwhelming, health tips we receive into manageable actions that we can implement.

(He’s also a talented musician and athlete, which may help explain his right-brain wholistic approach to health.) 

This episode is brought to you by:

➢ Try Somnifix.com, the world’s only hypoallergenic mouth tape, developed by Harvard Scientists.

https://www.somnifix.com

➢ Health IQ, an insurance company that helps health conscious people like weightlifters, cyclist, keto dieters and vegetarians get lower rates on their life insurance.

➢ Get a Free Quote: http://healthiq.com/HIH

 

You’ll learn more about:

-How to meditate, even if you’re mind is racing

-Electronic overuse (AKA screen time) as a disease promoter

-If you’re already low-carb, do you need to go even lower?

-Customizing your breakfast eating for blood sugar regulation

Direct download: 213_Rangan_Eric_Mix.mp3
Category:general -- posted at: 5:27pm PDT

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